What are the three fates of pyruvate that affect humans?

Sourav PanDecember 14, 2024

Answered

The three fates of pyruvate in humans are: 1) Conversion to Acetyl-CoA: In aerobic conditions, pyruvate is converted into acetyl-CoA, which enters the citric acid cycle to produce ATP. 2) Lactic Acid Fermentation: In anaerobic conditions (e.g., during exercise), pyruvate is converted to lactate, allowing glycolysis to continue by regenerating NAD+. 3) Amino Acid Synthesis: Pyruvate can be converted into alanine or other amino acids through transamination, contributing to protein synthesis and metabolic regulation.

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