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Biochemistry 9 Views 1 Answers

Sourav PanLv 9December 14, 2024

What are the roles of pyruvate dehydrogenase (PDH) and pyruvate carboxylase in metabolism?

What are the roles of pyruvate dehydrogenase (PDH) and pyruvate carboxylase in metabolism?

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Sourav PanLv 9May 15, 2025

Pyruvate dehydrogenase (PDH) catalyzes the conversion of pyruvate into acetyl-CoA while producing NADH and releasing CO2, linking glycolysis to the citric acid cycle. Pyruvate carboxylase (PC) converts pyruvate into oxaloacetate, which is important for gluconeogenesis and replenishing citric acid cycle intermediates.

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