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What are the 4 stages of DNA telomere replication?
What are the 4 stages of DNA telomere replication?
Answered
1. Extension of the 3′ overhang by telomerase: Telomerase adds repetitive nucleotide sequences to the 3′ end using an RNA template.
2. Synthesis of the complementary strand: DNA polymerase synthesizes the complementary strand to elongate the telomere.
3. Removal of the RNA primer: RNA primers used during replication are removed, creating gaps.
4. Re-sealing by ligase: DNA ligase seals the gaps in the DNA backbone, ensuring telomere integrity.
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