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Sourav PanNovember 14, 2024

Identify lymphocytes and phagocytes in photomicrographs and diagrams

Identify lymphocytes and phagocytes in photomicrographs and diagrams

Sourav Pan
Sourav PanNovember 14, 2024

Answered

To identify lymphocytes and phagocytes in photomicrographs and diagrams, here are the key characteristics and features of each type of cell based on the provided search results:

Lymphocytes

  1. Appearance:
    • Lymphocytes are generally smaller than phagocytes, with a diameter of about 7-15 micrometers.
    • They have a large, spherical nucleus that occupies most of the cell’s volume, with only a small amount of cytoplasm visible around the nucleus.
    • The cytoplasm typically appears as a thin blue rim in stained preparations.
  2. Types:
    • B Lymphocytes: Responsible for antibody production.
    • T Lymphocytes: Involved in cell-mediated immunity.
    • In photomicrographs, lymphocytes can be identified by their distinct large nucleus and minimal cytoplasm compared to other white blood cells.
  3. Identification in Images:
    • Look for cells with a prominent nucleus and scant cytoplasm. They will appear smaller than neutrophils and monocytes in blood smears.

Phagocytes

Phagocytes include various types of white blood cells that perform phagocytosis, primarily neutrophils and monocytes (which differentiate into macrophages).

  1. Neutrophils:
    • Appearance: Neutrophils are larger than lymphocytes, measuring about 12-14 micrometers in diameter. They have a multilobed nucleus, typically with 2-5 lobes connected by thin strands.
    • Their cytoplasm contains fine granules that stain pink or lavender.
  2. Monocytes:
    • Appearance: Monocytes are even larger, about 15-30 micrometers, with a kidney-shaped or horseshoe-shaped nucleus and abundant cytoplasm that appears grayish-blue.
    • They can differentiate into macrophages when they migrate into tissues.
  3. Identification in Images:
    • Look for neutrophils with their lobed nuclei and granules, which can be identified easily in stained blood smears.
    • Monocytes can be recognized by their large size and distinctive kidney-shaped nucleus.

Summary Table

Cell Type Size (µm) Nucleus Appearance Cytoplasm Appearance
Lymphocyte 7-15 Large, spherical Thin blue rim
Neutrophil 12-14 Multilobed Pink/lavender granules
Monocyte 15-30 Kidney-shaped Abundant grayish-blue

Resources for Visual Identification

For visual references and diagrams showing these cells:

  • TutorChase provides diagrams highlighting the differences between red blood cells, lymphocytes, and phagocytes .
  • Histology Guide offers photomicrographs that show lymphocytes and various types of phagocytes in detail .
  • Wikipedia has images illustrating the structure and function of white blood cells .
  • Kenhub includes histological images of lymphocytes and their roles in the immune system .
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