How does the Cori cycle relate to pyruvate and lactate metabolism?

Sourav PanDecember 14, 2024

Answered

The Cori cycle describes the metabolic pathway where lactate produced by anaerobic glycolysis in muscles is transported to the liver, where it is converted back into pyruvate by lactate dehydrogenase (LDH). This pyruvate can then enter gluconeogenesis to produce glucose, which can be released back into the bloodstream to replenish energy stores.

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