Does dioxiraybonewclese destroy hydrogen bases

nope, deoxyribonuclease (DNase) doesn’t destroy hydrogen bases directly. what it actually does—it breaks the phosphodiester bonds in the DNA backbone. so instead of attacking the nitrogenous bases (not hydrogen bases—bit of a mix-up maybe?), it cuts the sugar-phosphate chains between nucleotides.

the bases—adenine, thymine, guanine, cytosine—are still chemically intact, but once DNase cuts the strands, the DNA falls apart into smaller pieces or single nucleotides. the hydrogen bonds between complementary bases (like A–T or G–C) might break during this, but that’s more a side-effect of strand separation, not the main target. DNase’s job is to degrade DNA structure, not chemically modify the bases themselves.