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Sourav PanDecember 18, 2024

Are telomeres SINEs?

Are telomeres SINEs?

Sourav Pan
Sourav PanDecember 18, 2024

Answered

Telomeres are not classified as SINEs (Short Interspersed Nuclear Elements). SINEs are a type of transposable element found in the genome, characterized by short repetitive DNA sequences that can move around the genome through a “copy-and-paste” mechanism. In contrast, telomeres are repetitive DNA sequences found at the ends of chromosomes, which serve a protective function rather than a transposable one. The repetitive sequences in telomeres, such as TTAGGG in humans, are not mobile elements like SINEs. While both telomeres and SINEs consist of repetitive sequences, they serve very different roles in the genome—telomeres protect chromosome ends, while SINEs are thought to be relics of ancient retrotransposition events that may have had varying effects on genome evolution.

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