Questions and Answers

If the problem of the telomeres were not solved, what would happen?

A repeating DNA sequence at the end of chromosomes that prevents them from losing base pair sequences at their ends and from fusing together is—
– A telomere
– A telomerase
– A replicon
– A primer
– A promoter

All are part of a nucleotide except—
– Pentose sugar
– Nitrogenous base
– Phosphate group
– Fatty acid tail
– All of the above are parts of a nucleotide

The enzyme that stitches Okazaki fragments together on the lagging strand is—
– DNA polymerase II
– DNA polymerase III
– Topoisomerase
– DNA ligase
– DNA helicase

A DNA strand has the sequence 5′ ATCGTTATGCAA 3′. What would be the sequence of the complementary strand?

You made a mutation in your cells in which you inhibited the formation of Ligase enzyme. What will happen to the DNA replication in the cells?
– A. Nothing, DNA will replicate normally
– B. Semiconservative replication will not happen
– C. DNA primers will not form
– D. Replication bubble will not form

You synthesized a new peptide in your lab, which is permeable to the cell membrane. When you added it to eukaryotic cells, you noticed that the cells do not divide and eventually die. Upon further analysis, you discovered that a small replication bubble forms but does not last long, and the strands come back together. What molecules do you think are affected in your cells?
– A. Lysosome
– B. Polymerase I
– C. Polymerase III
– D. Topoisomerase
– E. Single-stranded binding proteins (SSBP)

What are the 4 stages of DNA telomere replication?

What functions do the two telomere-associated complexes, telomerase and shelterin, fulfill at chromosome ends?

Which statement is true regarding telomeres?

A. Telomeres are DNA segments at each end of a chromosome

B. Telomeres are antioxidants that slow the progress of senescence

C. Telomeres are motor molecules that guide embryonic cells to the right destinations

D. Telomeres are cytoplasmic enzymes involved in senescence

E. Telomeres are proteins that cap the ends of the chromosomes