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Sourav
23 Aug 2024

What will be the probability of having a colour-blind daughter to a phenotypically normal woman, who already had one colour-blind son, and is married to a colour-blind man? Options: (A) 75 % (B) 50 % (C) 25 % (D) 15%

What will be the probability of having a colour-blind daughter to a phenotypically normal woman, who already had one colour-blind son, and is married to a colour-blind man?
Options:
(A) 75 %
(B) 50 %
(C) 25 %
(D) 15%

1 Answer
Avatar for Sourav
Sourav
23 Aug 2024

What will be the probability of having a colour-blind son to a woman with phenotypically normal parents and a colour-blind brother, and married to a normal man? (Assume that she has no previous children) Options: (A) 100 % (B) 50 % (C) 25 % (D) 12.5 %

What will be the probability of having a colour-blind son to a woman with phenotypically normal parents and a colour-blind brother, and married to a normal man? (Assume that she has no previous children)
Options:
(A) 100 %
(B) 50 %
(C) 25 %
(D) 12.5 %

1 Answer
Avatar for Sourav
Sourav
23 Aug 2024

HAT (hypoxanthine, aminopterin and thymidine) is used for selecting the hybridomas based on the following: I. Only hybridoma will grow since it inherited the HGPRT genes from B-cells and can synthesize DNA from hypoxanthine. II. Myeloma cells will not grow in cultures since de novo synthesis is blocked by aminopterin and due to the lack of HGPRT enzyme. Options: (A) only I is true (B) only II is true (C) both I and II are true (D) I is true and II is false

HAT (hypoxanthine, aminopterin and thymidine) is used for selecting the hybridomas based on the following:
I. Only hybridoma will grow since it inherited the HGPRT genes from B-cells and can synthesize DNA from hypoxanthine.
II. Myeloma cells will not grow in cultures since de novo synthesis is blocked by aminopterin and due to the lack of HGPRT enzyme.
Options:
(A) only I is true
(B) only II is true
(C) both I and II are true
(D) I is true and II is false

1 Answer
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