For each of the following set of cells, state the latest common progenitor cel that gives rise to both cell types — ( i) Monocytes and neutrophils (ii) Natural killer cells and B cells.
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Infants immediately after birth are often at risk for infection with group B streptococcus. A vaccine is proposed for administration ot women of childbearing years. How can immunizing hte mothers, help hte babies?
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For each pair of antigens listed below, indicate which is likely to be more immunogenic. Explain your answer
(i) Insulin and Insulin-BSA conjugate.
(ii) A monomeric polypeptide (X) and a dimeric protein molecule
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What aer the two primary characteristics that distinguish hematopoietic stem cells and progenitor cells?
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An individual is infected with — i Intracellular bacteria and ii) Extracellular bacteria. Which kind(s) of immune response will be expected in each case?
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What are chemokines? Give one example.
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Explain briefly whether the following statements are true or false : (i) Dendritic cells arise only from the lymphoid organ. (ii) All TH cells express CD4 and recognize only antigen associated with class II MHC molecule. (iii) A hapten can stimulate antibody formation but cannot combine with many different antibody molecules. (iv) In order for B cells to mature into plasma cells, they need help from T cells. (v) All antigens are immunogens but all immunogens are not antigens.
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Most viruses and bacteria enter cells via specific receptors. Why would a cell have receptors that allow pathogens to enter?
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Which region of the whole MHC molecule shows the highest amino acid variation? What roles do anchor residues play in peptide binding by MHC molecules?
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What is the role of Mucosal-Associated Lymphoid Tissue (MALT) in host defence?
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