Determine the correctness or otherwise of the following Assertion (a) and the Reason (r):
Assertion: In synchronous culture, majority of the cells move to next phase of the cell cycle simultaneously.
Reason: Synchronous culture could be obtained by starving cells for essential nutrient components.
Options:
(A) both (a) and (r) are true and (r) is the correct reason for (a)
(B) both (a) and (r) are true but (r) is not the correct reason for (a)
(C) (a) is true but (r) is false
(D) (a) is false but (r) is true
1 Answer
Determine the correctness or otherwise of the following Assertion (a) and the Reason (r):
Assertion: Isopropylthiogalactoside (IPTG) is a gratuitous inducer of lactose operon.
Reason: Gratuitous inducers are chemical analogs which behave like natural inducers but they do not serve as substrate for the enzymes that are subsequently synthesized.
Options:
(A) both (a) and (r) are true and (r) is the correct reason for (a)
(B) both (a) and (r) are true but (r) is not the correct reason for (a)
(C) (a) is true but (r) is false
(D) (a) is false but (r) is true
1 Answer
Protein-protein interactions are studied by:
P. DNA foot printing
Q. Yeast two hybrid system
R. Ligase chain reaction
S. Mass spectrometry
Options:
(A) P and S only
(B) Q and S only
(C) P and R only
(D) Q and R only
1 Answer
Match the terms in Group I with their associated functions in Group II:
Group I
P. Shine-Dalgarno sequences
Q. Leucine zipper
R. Aminoacyl tRNA synthetase
S. RNA interference (RNAi)
Group II
1. Aminoacylation of tRNA
2. Gene silencing
3. Ribosome binding and facilitation of translation initiation
4. Transcription factors
Options:
(A) P-3, Q-4, R-1, S-2
(B) P-4, Q-3, R-2, S-1
(C) P-2, Q-3, R-1, S-4
(D) P-3, Q-2, R-4, S-1
1 Answer
Determine the correctness or otherwise of the following Assertion (a) and the Reason (r):
Assertion: A very low amount of inhibitor can act as an activator for allosteric enzymes.
Reason: Allosteric enzymes follow Michaelis-Menten kinetics.
Options:
(A) both (a) and (r) are true and (r) is the correct reason for (a)
(B) both (a) and (r) are true but (r) is not the correct reason for (a)
(C) (a) is true but (r) is false
(D) (a) is false but (r) is true
1 Answer
Determine the correctness or otherwise of the following Assertion (a) and the Reason (r):
Assertion: The elucidation of ribosome structure helps in the development of new generation drugs.
Reason: The high resolution of macromolecular structure has enabled in structure-based drug design.
Options:
(A) both (a) and (r) are true and (r) is the correct reason for (a)
(B) both (a) and (r) are true but (r) is not the correct reason for (a)
(C) (a) is true but (r) is false
(D) (a) is false but (r) is true
1 Answer
Match items in Group I with Group II:
Group I
P. Alzheimer’s disease
Q. Mad cow disease
R. Sickle cell anaemia
S. Swine flu
Group II
1. H1N1
2. Hemoglobin
3. Prions
4. Amyloid
Options:
(A) P-4, Q-3, R-2, S-1
(B) P-3, Q-4, R-1, S-2
(C) P-2, Q-1, R-4, S-3
(D) P-1, Q-2, R-3, S-4
1 Answer
Match items in Group I with Group II:
Group I
P. Glycolytic pathway
Q. Eukaryotic oxidative metabolism
R. Glyoxylate cycle
S. Calvin cycle
Group II
1. Chloroplast
2. Glyoxysomes
3. Mitochondria
4. Cytosol
Options:
(A) P-1, Q-2, R-3, S-4
(B) P-2, Q-3, R-4, S-1
(C) P-4, Q-3, R-2, S-1
(D) P-3, Q-4, R-1, S-2
1 Answer
Structured William’s model:
P. can describe the changes in intracellular components of the cell during growth
Q. can not describe the death phase of the cells
R. can describe the variation of size of cells in the different phases of growth
S. can not describe the lag period of growth
Options:
(A) P, Q and S only
(B) P, Q and R only
(C) Q, R and S only
(D) P, R and S only
1 Answer
In a well-aerated and agitated microbial culture, the ‘supply’ of oxygen is equal to demand:
C = instantaneous value of dissolved oxygen concentration
T = specific oxygen uptake rate per unit weight of cells
X = dry weight of the cells per unit volume
Options:
(A) (r X) / (C*- C)
(B) (r) / X (C*- C)
(C) (C”- C) / (r X)
(D) (X) / r (C*- C)
1 Answer
