State that the exact replication of chromosomes occurs before mitosis

Before mitosis begins, an essential process known as DNA replication occurs, ensuring that chromosomes are exactly duplicated. This replication takes place during the S phase (synthesis phase) of interphase, which precedes mitosis in the cell cycle.

Key Points about Chromosome Replication

• Exact Duplication: During DNA replication, each chromosome is copied precisely, resulting in two identical sister chromatids for each chromosome. This ensures that both daughter cells will receive an identical set of genetic information.
• Preparation for Mitosis: The accurate replication of chromosomes is crucial for the successful division of genetic material during mitosis. Without this step, daughter cells would not have the correct number of chromosomes, leading to genetic abnormalities.
• Chromatin to Chromosome Transition: After replication, the chromatin condenses into distinct chromosomes, making it easier to segregate them during mitosis.