How do prions infect?
How do prions infect?
Cite this post:
Sourav Pan. (2024, September 6). How do prions infect?. Biology Notes Online. Retrieved from https://biologynotesonline.com/qa/how-do-prions-infect/
Sourav Pan. "How do prions infect?." Biology Notes Online, 6 September 2024, biologynotesonline.com/qa/how-do-prions-infect/.
Sourav Pan. "How do prions infect?." Biology Notes Online (blog). September 6, 2024. https://biologynotesonline.com/qa/how-do-prions-infect/.
Answered
Prions infect by converting normal prion proteins (PrP^C) in the host into the abnormal, disease-causing form (PrP^Sc). This conversion process is initiated when a prion encounters a normal protein, causing it to misfold and adopt the abnormal prion structure. The newly formed prions then go on to induce further misfolding of other normal prion proteins, creating a cascade of abnormal protein accumulation. This process disrupts cellular function, leads to neuronal damage, and results in the progressive neurodegeneration characteristic of prion diseases.
Cite this post:
Sourav Pan. (2024, September 6). How do prions infect?. Biology Notes Online. Retrieved from https://biologynotesonline.com/qa/how-do-prions-infect/
Sourav Pan. "How do prions infect?." Biology Notes Online, 6 September 2024, biologynotesonline.com/qa/how-do-prions-infect/.
Sourav Pan. "How do prions infect?." Biology Notes Online (blog). September 6, 2024. https://biologynotesonline.com/qa/how-do-prions-infect/.
