Biological Weapons History Timeline

1346 - 2001 11 events
biological warfare

Siege of Caffa

1346
Mongols catapulted plague-infected bodies into Caffa spreading the Black Death in Europe
early biological warfare

Hittite Use of Tularemia

1500-1200
Hittites allegedly drove tularemia-infected victims into enemy lands causing epidemics
biological warfare

Pontiac’s Rebellion

1763
British soldiers gave smallpox-infected blankets to Native American tribes as biological warfare
military biowarfare

German Anthrax Sabotage

1914-1918
Germany used anthrax to infect Allied livestock during World War I
war crimes

Japanese Unit 731 Experiments

1930s-1945
Japan conducted biological warfare experiments using plague and anthrax on prisoners
bioterrorism experiment

Operation Sea-Spray

1950
U.S. Navy secretly released bacteria over San Francisco to test vulnerability to bioweapons
military testing

Project 112

1962-1973
U.S. conducted biological and chemical weapons tests including on naval ships
bioweapons testing

Aral Smallpox Incident

1971
Soviet biological weapons test caused a smallpox outbreak resulting in deaths
production

Biological Weapons Convention

1975
Treaty banning development
accidental release

Sverdlovsk Anthrax Leak

1979
Accidental release of anthrax spores from Soviet facility causing multiple deaths
bioterrorism

2001 Anthrax Attacks

2001
Anthrax spores sent through U.S. mail causing deaths and infections
1346 1500-1200 1763 1914-1918 1930s-1945 1950 1962-1973 1971 1975 1979 2001

Biological Weapons History Timeline

Title Date Era Description Category
Hittite Use of Tularemia 1500–1200 BCE Ancient Civilizations Hittites allegedly drove victims of tularemia into enemy lands, causing epidemics. Early Biological Warfare
Siege of Caffa 1346 CE Medieval Period Mongols catapulted plague-infected bodies into Caffa, initiating the Black Death in Europe. Biological Warfare
Pontiac’s Rebellion 1763 CE Colonial Period British soldiers gave smallpox-infected blankets to Native American tribes. Biological Warfare
German Anthrax Sabotage 1914–1918 CE World War I Germany conducted sabotage operations using anthrax to infect Allied livestock. Military Biowarfare
Japanese Unit 731 Experiments 1930s–1945 CE World War II Japan conducted biological warfare experiments on prisoners, including plague and anthrax. War Crimes
Operation Sea-Spray 1950 CE Cold War U.S. Navy secretly released bacteria over San Francisco to study vulnerability to bioweapons. Bioterrorism Experiment
Project 112 1962–1973 CE Cold War U.S. conducted biological and chemical weapon tests, including on warships. Military Testing
Sverdlovsk Anthrax Leak 1979 CE Cold War Accidental release of anthrax spores from a Soviet facility, causing at least 68 deaths. Accidental Release
Aral Smallpox Incident 1971 CE Cold War Soviet test of smallpox virus led to an outbreak, resulting in 3 deaths. Bioweapons Testing
Biological Weapons Convention 1975 CE Post-Cold War Treaty banning the development, production, and stockpiling of biological weapons. Disarmament Treaty
Sverdlovsk Anthrax Leak 1979 CE Cold War Accidental release of anthrax spores from a Soviet facility, causing at least 68 deaths. Accidental Release
2001 Anthrax Attacks 2001 CE Early 21st Century Anthrax spores sent through U.S. mail, resulting in 5 deaths and 17 infections. Bioterrorism
2001 Anthrax Attacks 2001 CE Early 21st Century Anthrax spores sent through U.S. mail, resulting in 5 deaths and 17 infections. Bioterrorism
2001 Anthrax Attacks 2001 CE Early 21st Century Anthrax spores sent through U.S. mail, resulting in 5 deaths and 17 infections. Bioterrorism
2001 Anthrax Attacks 2001 CE Early 21st Century Anthrax spores sent through U.S. mail, resulting in 5 deaths and 17 infections. Bioterrorism

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