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what is motility in biology at its core
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motility is the fundamental capacity for
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autonomous movement in biological
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organisms motility is defined as the
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ability of organisms or cells to move
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independently using metabolic energy
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motility differs from passive movement
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in several key ways active motility
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requires metabolic energy and is
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self-directed and purposeful in contrast
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passive movement relies on external
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forces requires no energy expenditure
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and lacks directional
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control motility operates across
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multiple biological scales at the
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cellular level motility includes
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movements of individual cells using
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structures like fleella or psyia at the
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organism level motility involves
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coordinated movements of muscles and
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appendages and at the population level
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motility can involve migration patterns
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and collective movement
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behaviors understanding motility is
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crucial to biology for several reasons
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motility allows organisms to acquire
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essential resources like food water and
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nutrients it enables creatures to escape
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predators and other threats motility is
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essential for finding mates and
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successful reproduction it allows
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species to explore and colonize new
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environments and at the cellular level
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motility is critical for immune
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responses and developmental processes as
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we conclude our introduction to
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biological motility let's review the key
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concepts motility is autonomous movement
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powered by metabolic energy distinct
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from passive movement that relies on
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external forces it functions across
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multiple biological scales and is
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essential for survival reproduction and
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muscular movement is a primary form of
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motility in animals enling everything
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from simple actions to complex
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locomotion muscles are composed of
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specialized fibers containing protein
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filaments called actin and meosin inside
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each muscle fiber are thousands of
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sarccomirs the basic functional units of
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muscles muscle contraction occurs
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through the sliding filament mechanism
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where actin and meosin filaments overlap
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and slide past each other
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the crossbridge cycle is powered by ATP
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which provides energy for muscle
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contraction this cycle involves ATP
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binding hydraysis crossbridge formation
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the power stroke and release of
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byproducts these molecular contractions
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translate to coordinated movements in
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complex organisms for example human
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walking involves the coordinated
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contraction of multiple muscle groups to
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create a smooth balanced gate while a
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bird's flight relies on rapid wing
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muscles that contract in precise
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sequences to generate lift and
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propulsion muscular movement requires
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significant energy input primarily in
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the form of ATP generated from glucose
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metabolism the conversion of chemical
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energy to mechanical work is remarkably
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efficient in muscles but still results
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muscles exhibit remarkable adaptability
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in balancing energy efficiency with
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performance requirements from the
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molecular level to complex coordinated
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movements muscular contraction enables
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the diverse forms of locomotion we see
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throughout the animal kingdom hydraulic
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movement represents one of nature's most
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elegant solutions for creating motion
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without traditional muscles hydraulic
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systems work using incompressible fluids
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under pressure when force is applied to
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one part of a closed fluid system that
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pressure is transmitted equally
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throughout the entire
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system spiders offer a fascinating
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example of hydraulic movement unlike
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vertebrates spiders lack extensor
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muscles in their legs instead they pump
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hemolymph their equivalent of blood into
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their legs to extend them through
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pressure sea stars demonstrate another
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remarkable hydraulic system they use
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what's called a water vascular system
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with tube feet controlled by fluid fil
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ampy when an impella contracts it forces
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water into the tube foot extending it
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attachment compared to muscular movement
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hydraulic systems have distinct
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advantages and limitations they're
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simpler with fewer components and can
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transmit force efficiently however they
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typically have slower response times and
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are vulnerable to leaks despite these
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trade-offs hydraulic movement represents
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a fascinating evolutionary solution that
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has evolved independently in several
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groups fleeller motility is a remarkable
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form of cellular propulsion that allows
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microscopic organisms to move through
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environments fleella are whip-like
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structures that extend from the cell
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body there are two distinct types the
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complex ukareotic fugellum and the
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simpler proaryotic flegellum ukarotic
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fugella found in human sperm cells
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contain a complex arrangement of
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microtubules proarotic fugella seen in
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bacteria like ecoli consist of a rotary
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motor at the base connected to a rigid
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filament the movement mechanism differs
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dramatically between the two types of
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fugella ukareotic fugella create a
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wavelike motion through the sliding of
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internal microtubules powered by motor
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dinines in contrast proaryotic fugella
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operate like a tiny rotary motor
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spinning the rigid filament to create a
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corkcrew motion that propels the
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forward let's see fleeller motility in
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action with two key examples first human
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sperm cells use their single powerful
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flegellum to swim toward the egg sperm
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navigate by detecting chemical gradients
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released by the egg a process called
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chemotaxis their flegellum creates a
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powerful asymmetric wave that propels
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them through the female reproductive
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tract bacteria like E.coli use multiple
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fleella that can rotate in coordination
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to achieve directed movement bacteria
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move using a run and tumble strategy
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during runs fugella rotate
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counterclockwise in synchrony pushing
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the cell forward when fleella rotate
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clockwise they cause the bacterium to
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direction let's examine the remarkable
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precision and efficiency of these
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microscopic propulsion systems despite
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their tiny size flagagillated cells
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achieve impressive speeds sperm can
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travel about five body lengths per
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second while bacteria can move at speeds
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of up to 10 body lengths per second even
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more remarkable is their navigation
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precision bacteria can detect chemical
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concentration changes of less than 1%
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allowing them to efficiently navigate
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toward nutrients or away from toxins
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fleeller motility demonstrates nature's
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ability to create efficient precise
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propulsion systems at the microscopic
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scale enabling cells to navigate their
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environments with remarkable
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amiioid movement represents one of
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nature's most flexible forms of cellular
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locomotion in this remarkable form of
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movement cells dynamically change their
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shape by extending and retracting
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temporary projections called pseudopodia
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or false feet pseudopodia are extensions
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of the cell membrane that allow
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directional movement similar to a foot
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reaching forward to take a step
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the key to amiioid movement is the
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dynamic rearrangement of the cell's
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cytokeleton primarily composed of actin
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filaments this movement involves three
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key processes actin polymerization
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pushes the membrane forward meiosin
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contraction pulls the rear of the cell
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and their coordinated assembly and
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disassembly creates directional
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motion amoboid movement is found in
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several types of cells throughout nature
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free living amiebas use this movement to
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navigate their aquatic environments in
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search of food white blood cells employ
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amiioid movement to chase and engulf
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pathogens during immune responses some
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cancer cells utilize amiioid movement
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during metastasis allowing them to
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migrate through tissues and spread to
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body a key advantage of amuoid movement
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is the ability to navigate through
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cells can squeeze through tight spaces
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and change direction rapidly as they
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encounter barriers in their
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environment ameboid movement plays
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crucial roles in both normal physiology
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and disease states in normal physiology
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it enables immune cell migration
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contributes to wound healing and is
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essential for various aspects of
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embryionic development however in
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pathological conditions this same
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movement mechanism can facilitate cancer
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metastasis contribute to chronic
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inflammation and enable certain invasive
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infections ultimately amiboid movement
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represents one of biologyy's most
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versatile forms of cellular motility
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enabling cells to adapt to and navigate
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through incredibly diverse environments
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bacteria have evolved specialized forms
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of movement beyond the well-known
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fleeller motion two fascinating
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mechanisms are swarming and gliding
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motility swarming motility involves the
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coordinated movement of bacterial
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populations across surfaces these
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bacteria move as a collective creating
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distinctive patterns during swarming
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bacteria produce surfactants and use
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their fleella in a coordinated fashion
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this allows them to rapidly colonize
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surfaces and form bofilms in contrast
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gliding motility allows bacteria to move
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smoothly across surfaces without any
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visible propulsion structures like
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fleella gliding bacteria use molecular
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motors and focal adhesion complexes as
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they move many leave behind slime trails
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that can aid in colony
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formation at the molecular level both
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types of motility rely on complex
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protein machinery molecular motors
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generate force through confirmational
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changes in protein structures focal
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adhesion complexes act as anchors
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attaching to surfaces and allowing the
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bacteria to pull themselves forward in a
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crawling these specialized forms of
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motility have profound ecological
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significance they enable bacteria to
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colonize new habitats and adapt to
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changing environments through swarming
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and gliding bacteria can form structured
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bofilms complex communities that provide
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protection and increased resistance to
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antibiotics recent research has revealed
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the remarkable complexity of these
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movements scientists have discovered
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sophisticated genetic regulatory
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networks that control swarm behavior we
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now understand that bacteria use
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chemical signals to communicate with
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each other allowing them to coordinate
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their movements as a
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collective these motility mechanisms
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also play crucial roles in host pathogen
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interactions and bacterial survival in
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diverse environments understanding the
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molecular basis of bacterial motility
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has opened new possibilities for
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developing innovative antibiotics that
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target these movement mechanisms in
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conclusion bacterial swarming and
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gliding demonstrate that even the
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simplest forms of life have evolved
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sophisticated movement strategies these
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motility mechanisms showcase the
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remarkable complexity and adaptability
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life motility plays a crucial role in
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both survival and reproductive success
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across the animal kingdom
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predator prey interactions often come
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down to a contest of speed and agility
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the ability to move faster or change
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direction more efficiently can mean the
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difference between life and death for
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example cheetahs can reach speeds of up
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to 100 km hour to catch gazels meanwhile
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prey species have evolved erratic
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movement patterns that make them harder
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to predict and catch
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migration requires incredibly efficient
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movement over vast distances animals
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travel thousands of kilometers to access
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seasonal resources and breeding grounds
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arctic turns hold the record for the
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longest migration flying 71,000 km
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annually between the Arctic and
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Antarctic grey whales travel 22,000 km
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between feeding grounds and breeding
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reproductive success often depends
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directly on mobility in many species
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sperm cells must swim efficiently to
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reach and fertilize eggs sperm
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competition is fierce with the most
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modal cells having the best chance of
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success the fastest and most efficient
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swimmers typically fertilize the egg
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plant reproduction also depends on
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mobility but often through relationships
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with pollinators bees and other insects
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transport pollen between flowers
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reproduction movement requires a
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significant energy investment different
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forms of motility have varying energy
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costs flying is typically the most
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energyintensive form of movement
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followed by running and swimming walking
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is generally more efficient for motility
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to evolve and persist its benefits must
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outweigh its costs the energy invested
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must provide proportional advantages in
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reproduction throughout evolutionary
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history selective pressures have shaped
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diverse motility mechanisms to maximize
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both survival and reproductive
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success immune cell motility is
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fundamental to human health white blood
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cells such as neutrfils and macrofasages
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actively migrate to sites of infection
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or injury this directed movement called
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chemotaxis is guided by chemical signals
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from damaged tissues or
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pathogens sperm motility is critical for
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fertility healthy sperm cells use their
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fleella to propel themselves through the
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female reproductive tract this journey
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can span over 15 cm and requires both
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motility and endurance to reach the egg
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gastrointestinal motility is essential
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for proper digestion the digestive tract
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uses a process called paristelis
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coordinated muscle contractions that
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propel food from the esophagus through
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the stomach and intestines this rhythmic
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movement ensures food is properly mixed
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with digestive enzymes and moves at the
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correct pace for optimal nutrient
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motility disorders occur when normal
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malfunction in imotiles cyia syndrome
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psyia in the respiratory tract fail to
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move properly preventing the clearance
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of mucus and pathogens gastroparesis is
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a condition where stomach muscles don't
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function properly delaying emptying and
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causing symptoms like nausea and
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both pathogens and cancer cells can
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exploit motility mechanisms to cause
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disease invasive bacteria use fugella
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and other motility structures to
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penetrate tissues and evade immune
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responses cancer cells that develop
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enhanced motility capabilities can
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metastasize breaking away from the
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primary tumor and spreading to distant
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body understanding motility mechanisms
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has led to numerous medical
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for fertility issues treatments can
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enhance sperm motility or bypass
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motility requirements through techniques
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fertilization gastrointestinal motility
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disorders are treated with medications
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that either stimulate or inhibit muscle
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contractions depending on the condition
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researchers are developing anti-tastatic
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therapies that target cancer cell
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motility mechanisms to prevent spread
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for respiratory disorders like imotile
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celia syndrome therapies help compensate
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for poor mucosiliary
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clearance the ability to move has
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profoundly shaped the course of
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evolution and the diversity of life on
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Earth from the earliest simple cellular
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movements to complex migration patterns
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motility has steadily evolved over
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the ability to move allowed organisms to
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explore and adapt to new environments
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this opened up ecological niches that
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inaccessible predator prey relationships
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created an evolutionary arms race of
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movement faster predators selected for
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quicker prey and more agile prey
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required better hunters driving
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co-evolution motility doesn't exist in
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isolation it connects intimately with
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other biological systems movement
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requires energy from metabolism guidance
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from sensation and serves the ultimate
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reproduction from microscopic cellular
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movements to global migrations motility
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remains one of the most fundamental and
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fascinating aspects of life on Earth the
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ability to move has not only shaped our
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planet's biodiversity but continues to
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drive evolution today