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what are non-communicable diseases or
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ncds non-communicable diseases are
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medical conditions that cannot be
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transmitted from person to person unlike
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infectious diseases such as the flu or
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covid 19 ncds cannot spread through
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contact ncds are typically chronic in
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nature meaning they last for long
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periods of time and progress
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gradually these diseases result from a
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combination of four main factors genetic
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factors which include hereditary
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predispositions passed down through
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families physiological factors such as
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high blood pressure or obesity
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environmental influences including air
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pollution and workplace hazards and
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behavioral factors such as tobacco use
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physical inactivity and poor
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diet the global impact of ncds is
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staggering they account for 74% of all
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deaths worldwide making them by far the
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leading cause of mortality globally
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the four major categories of ncds are
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cardiovascular diseases which affect the
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heart and blood vessels cancer
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characterized by abnormal cell growth
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chronic respiratory diseases which
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impact the lungs and airways and
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diabetes a metabolic disorder affecting
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blood sugar regulation
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understanding these non-communicable
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diseases is crucial for developing
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effective prevention and management
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strategies cardiovascular diseases are a
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major category of non-communicable
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diseases affecting the heart and blood
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vessels common cardiovascular conditions
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include heart disease which involves
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narrowed or blocked coronary arteries
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stroke occurs when blood flow to the
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brain is blocked causing brain cell
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death hypertension or high blood
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pressure damages blood vessels over time
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and is a major risk factor for other
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diseases cardiovascular diseases affect
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how blood flows through your vessels in
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a healthy blood vessel blood flows
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freely in a diseased blood vessel plaque
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buildup and narrowing restrict blood
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flow reducing oxygen delivery to vital
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organs this restriction of blood flow
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can lead to tissue damage and impaired
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several key risk factors increase the
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likelihood of developing cardiovascular
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diseases high blood pressure puts stress
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on artery walls making them more
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susceptible to damage high cholesterol
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leads to plaque buildup in blood vessels
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smoking damages blood vessels and
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reduces oxygen in the blood and obesity
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increases strain on the heart and is
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linked to high blood pressure and
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diabetes these modifiable risk factors
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account for over 90% of cardiovascular
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risk cardiovascular diseases have an
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enormous global impact they are the
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number one cause of death globally among
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all non-communicable diseases cvds
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account for 32% of all global deaths
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compared to 16% for cancer respiratory
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diseases and diabetes account for 7 and
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4% respectively this translates to
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approximately 17.9 million deaths
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annually from cardiovascular
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diseases cancer is a major category of
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non-communicable diseases characterized
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by abnormal cell growth with the
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potential to invade or spread to other
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body let's look at the difference
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between normal and cancer cells normal
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cells grow in a controlled manner with
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organized structure they die when
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damaged and stay where they belong
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cancer cells however grow uncontrollably
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with irregular structures they resist
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normal cell death signals and can invade
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tissues the most common types of cancer
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include lung cancer which is the leading
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cause of cancer deaths worldwide breast
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cancer is the most commonly diagnosed
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cancer in women colorectal cancer is the
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third most common cancer globally and
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prostate cancer is the most common
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men cancer develops through genetic
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mutations that affect the cell's growth
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and division mechanisms this process
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typically starts with a normal cell that
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acquires a genetic mutation leading to
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abnormal growth cancer formation and
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metastasis metastasis is the process by
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which cancer spreads from its original
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site to other parts of the body this
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occurs when cancer cells break away from
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the primary tumor travel through the
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bloodstream or lymphatic system and form
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new tumors in distant
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locations several key risk factors
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contribute to cancer development tobacco
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use is the leading preventable cause of
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cancer worldwide unhealthy diets
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particularly those high in processed
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foods and fats can increase cancer risk
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physical inactivity and sedentary
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lifestyles are associated with higher
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exposure to carcinogens such as certain
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chemicals uv radiation and asbestous can
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damage dna and lead to
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cancer early detection is crucial for
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successful cancer treatment and improved
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survival rates mammogs are recommended
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for women aged 40 to 50 and older every
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1 to two years to detect breast cancer
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colonoscopies are recommended for adults
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45 and older every 10 years to detect
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colurectal cancer psa tests for men 50
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and older can help detect prostate
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cancer though the decision to test
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should be discussed with a
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doctor chronic respiratory diseases are
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long-term conditions that affect the
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airways and lungs making breathing
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progressively more difficult these
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diseases impact the respiratory system
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which includes the airways lungs and the
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muscles that enable breathing
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copd or chronic obstructive pulmonary
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disease is a progressive condition that
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makes breathing difficult due to
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inflammation and damage to lung tissue
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in copd the airways become inflamed and
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narrowed and the air sacks in the lungs
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destroyed the primary risk factor for
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copd is tobacco smoke responsible for up
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to 80% of cases worldwide other risk
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factors include exposure to air
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pollution occupational dusts and
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chemicals and certain genetic factors
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like alpha 1 antitrien
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deficiency copd significantly impacts
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quality of life through symptoms such as
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shortness of breath persistent cough
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with mucus production and wheezing as
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the disease progresses even simple
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activities like walking climbing stairs
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or performing daily tasks become
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asthma is another major chronic
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respiratory disease where the airways
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become inflamed narrow and swollen
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making breathing difficult during an
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asthma attack the muscles around the
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airways tighten the airway lining
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becomes inflamed and excess mucus is
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produced significantly narrowing the air
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passages unlike copd asthma has both
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genetic and environmental triggers
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environmental factors include allergens
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like pollen dust mites and pet dander as
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well as air pollution cold air and
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respiratory infections genetic factors
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also play a significant role in asthma
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development with family history being a
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strong predictor of the
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condition asthma symptoms include
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shortness of breath chest tightness
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wheezing during exhalation and coughing
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attacks particularly at night or during
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physical activity these symptoms can
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significantly impact quality of life
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causing activity limitations sleep
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disturbances school or work absences and
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sometimes requiring emergency medical
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attacks both copd and asthma are major
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chronic respiratory diseases but they
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differ in key ways copd is progressive
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and largely irreversible primarily
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caused by tobacco smoke and develops
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slowly over years asthma on the other
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hand is characterized by episodic and
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often reversible symptoms has multiple
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environmental and genetic triggers and
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can develop at any age though it's more
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children diabetes is a metabolic
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disorder characterized by high blood
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sugar levels this occurs when the body
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either doesn't produce enough insulin or
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can't effectively use the insulin it
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produces insulin produced by the
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pancreas is critical for regulating
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blood sugar it allows cells to take in
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glucose from the bloodstream and use it
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energy there are two main types of
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diabetes type one is an autoimmune
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condition where the body attacks and
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destroys insulin producing cells in the
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pancreas type 2 diabetes is when the
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body becomes resistant to insulin or
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doesn't produce enough it's often
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associated with lifestyle factors and
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typically develops in adulthood though
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it's increasingly seen in younger
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populations diabetes affects multiple
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body systems and can lead to serious
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complications if not properly managed
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cardiovascular complications are common
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increasing the risk of heart attack and
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stroke kidney disease or diabetic
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nephropathy is a serious complication
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and a leading cause of kidney failure
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diabetic retinopathy can damage blood
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vessels in the retina potentially
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leading to vision loss or blindness
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nerve damage or diabetic neuropathy can
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cause pain numbness and increase the
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risk of infections especially in the
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feet let's examine the key risk factors
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for type 2 diabetes which accounts for
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about 90% of all diabetes cases
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worldwide obesity especially abdominal
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obesity is strongly linked to insulin
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resistance a bmi over 30 significantly
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increases risk physical inactivity
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reduces the body's ability to use
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insulin effectively less than 150
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minutes of moderate activity per week
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increases risk poor diet particularly
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one high in processed foods sugars and
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unhealthy fats contributes to weight
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gain and affects blood glucose
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regulation genetic factors play a role
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too having a first-degree relative with
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type 2 diabetes increases your risk
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between two and six times age is another
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factor with risk increasing after age 45
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other risk factors include ethnicity
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gestational diabetes history and certain
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conditions diabetes has become a global
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epidemic with prevalence rising
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dramatically over the past few decades
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according to the international diabetes
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federation as of 2021 approximately 537
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million adults are living with diabetes
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worldwide and this number is projected
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to reach 783 million by 2045 the burden
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is particularly heavy in developing
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countries with three in four people with
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diabetes living in low and middle inome
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countries what's particularly concerning
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is that approximately one in two adults
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with diabetes remain undiagnosed
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increasing their risk of developing
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complications while cardiovascular
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diseases cancer respiratory conditions
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and diabetes often dominate discussions
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of non-communicable diseases several
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other major ncds affect millions
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worldwide neurological disorders affect
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the brain and nervous system alzheimer's
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disease causes progressive memory loss
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and cognitive decline affecting over 50
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million people worldwide parkinson's
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disease affects movement control causing
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tremors rigidity and balance problems it
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impacts over 10 million people globally
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and progressively worsens over
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time muscularkeeletal conditions affect
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the joints bones and supporting tissues
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arthritis involves joint inflammation
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and pain affecting over 350 million
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people and causing significant
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disability osteoporosis causes bone
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density loss making bones fragile and
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prone to fracture it affects more than
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200 million people worldwide
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adults chronic kidney disease involves
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the progressive loss of kidney function
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it affects approximately 10% of the
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global population and can eventually
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require dialysis or kidney
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transplantation ckd progresses through
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stages as kidney function gradually
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declines it's both a consequence of and
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contributor to other ncds particularly
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disease the global impact of these ncds
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is substantial with hundreds of millions
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affected worldwide chronic kidney
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disease affects nearly 850 million
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people while arthritis impacts over 350
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million these conditions place an
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enormous burden on health care systems
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worldwide through increased
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hospitalization rates and long-term care
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needs they also significantly reduce
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quality of life and workforce
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while these conditions often receive
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less attention than cardiovascular
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disease or cancer they affect hundreds
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of millions worldwide and require
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comprehensive healthcare
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strategies risk factors for
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non-communicable diseases can be divided
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into three main categories modifiable
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risk factors that we can change through
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behavior environmental risk factors from
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our surroundings and non-modifiable risk
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factors like age and genetics
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modifiable risk factors are behaviors we
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can change to reduce our risk of
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developing ncds tobacco use
13:47
significantly increases the risk of lung
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cancer heart disease and chronic
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respiratory conditions even secondhand
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smoke exposure is dangerous physical
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inactivity contributes to obesity and
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heart disease while also weakening our
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immune system and decreasing overall
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health an unhealthy diet high in
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processed foods sugar and salt while low
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in fruits and vegetables increases risk
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for multiple ncds including diabetes and
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heart disease the harmful use of alcohol
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damages the liver and contributes to
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several cancers and cardiovascular
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diseases even at moderate consumption
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levels it's important to understand that
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these behavioral factors often
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contribute to multiple ncds
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simultaneously for instance smoking
14:30
affects both heart and lung health
14:35
environmental risk factors are hazards
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in our surroundings that increase our
14:39
risk of developing ncds air pollution
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both indoor and outdoor significantly
14:44
contributes to respiratory diseases lung
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cancer and cardiovascular problems the
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wh estimates that air pollution is
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responsible for millions of premature
14:54
deaths annually workplace exposures to
14:57
chemicals dust radiation and other
14:59
hazardous materials are linked to
15:01
various cancers respiratory conditions
15:04
and other health problems certain
15:06
industries have higher risks of specific
15:10
ncds non-modifiable risk factors are
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aspects we cannot change but must be
15:15
aware of to understand our complete risk
15:18
profile age is a major risk factor for
15:20
most ncds as we get older cellular
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damage accumulates and our bodies become
15:25
less efficient at repair increasing
15:27
disease risk genetics play a significant
15:30
role in ncd risk certain genetic
15:32
variations can increase susceptibility
15:34
to diseases like type 2 diabetes certain
15:37
cancers and heart conditions family
15:40
history often indicates shared genetic
15:42
and environmental factors having close
15:44
relatives with ncds like heart disease
15:46
or cancer increases your personal risk
15:51
the good news is that addressing
15:53
modifiable risk factors can have a
15:55
tremendous impact on disease prevention
15:58
research shows that addressing
16:00
modifiable risk factors could prevent up
16:02
to 80% of heart disease stroke and type
16:05
2 diabetes cases worldwide these four
16:08
modifiable factors tobacco use physical
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inactivity unhealthy diet and harmful
16:14
alcohol use have the greatest impact on
16:17
ncd prevention and should be primary
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targets for both personal and public
16:23
interventions prevention strategies are
16:25
crucial in reducing the global burden of
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non-communicable diseases prevention
16:30
strategies fall into four main
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categories health promotion and
16:34
education creating supportive
16:36
environments policy interventions and
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encouraging healthy individual
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behaviors health promotion and education
16:45
campaigns are essential for raising
16:47
awareness about ncds and their risk
16:49
factors these include public awareness
16:51
campaigns school-based education
16:54
community outreach and digital health
16:59
creating supportive environments makes
17:01
healthy choices easier for people this
17:04
includes providing accessible
17:05
recreational spaces implementing
17:08
workplace wellness programs establishing
17:10
smoke-free zones and ensuring healthy
17:16
schools policy interventions are
17:18
powerful tools governments use to
17:21
influence health behaviors on a
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population level these include tobacco
17:25
taxes and plain packaging alcohol
17:28
minimum pricing and age restrictions and
17:30
food labeling requirements and sugar
17:32
taxes these policies can lead to
17:34
significant populationwide improvements
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in ncd risk factors with tobacco
17:39
interventions showing the highest
17:43
impact individual health behaviors play
17:46
a critical role in ncd prevention the
17:48
four key behaviors include regular
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physical activity balanced nutrition
17:53
avoiding tobacco products and limiting
17:55
alcohol consumption health guidelines
17:58
recommend at least 150 minutes of
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moderate exercise weekly five or more
18:03
servings of fruits and vegetables daily
18:06
complete avoidance of tobacco products
18:08
and limited alcohol consumption
18:12
prevention strategies for ncds are
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significantly more cost-effective than
18:17
treatment on average prevention
18:19
interventions cost around $5,000 per
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quality adjusted life year gained
18:24
compared to $15,000 for treatment
18:27
studies consistently show that
18:29
prevention strategies are approximately
18:31
three times more cost-effective than
18:34
treatment approaches for reducing the
18:36
global burden of non-communicable
18:43
the growing burden of non-communicable
18:45
diseases requires coordinated global
18:47
action across multiple sectors and
18:50
stakeholders currently 85% of premature
18:53
ncd deaths occur in low and middle inome
18:56
countries ncds are responsible for over
18:58
41 million deaths annually worldwide
19:01
with 15 million people between the ages
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of 30 and 69 dying prematurely
19:08
the world health organization
19:09
established the global action plan for
19:11
ncds with the ambitious goal of a 25%
19:14
reduction in premature ncd mortality by
19:18
2025 known as the 25 by 25 target this
19:21
comprehensive plan focuses on key areas
19:24
including reducing exposure to risk
19:26
factors strengthening health systems
19:28
monitoring trends and promoting research
19:33
strengthening health systems is crucial
19:35
for addressing ncds particularly in low
19:37
and middle inome countries effective
19:40
health systems require robust primary
19:42
care access trained healthare workers
19:45
availability of essential medicines
19:47
functional data systems and sustainable
19:49
financing mechanisms there must be a
19:52
priority focus on low and middle inome
19:54
countries where the burden of ncds is
19:56
growing most rapidly and resources are
20:01
constrained emerging technologies and
20:03
innovations are revolutionizing how we
20:06
address ncds globally mobile health
20:08
solutions artificial intelligence
20:10
wearable devices and tele medicine are
20:13
expanding access to prevention and care
20:15
services even in remote areas these
20:18
technologies are transforming how we
20:19
approach ncd prevention early diagnosis
20:22
and management making health care more
20:27
personalized addressing ncds is
20:29
essential for achieving the sustainable
20:31
development goals sdg target 3.4
20:34
specifically calls for reducing
20:36
premature mortality from ncds by
20:38
onethird by 2030 ncd prevention and
20:41
control supports multiple development
20:43
goals by reducing poverty and inequality
20:45
promoting economic growth strengthening
20:48
health systems and advancing gender
20:52
equality in conclusion addressing the
20:55
growing burden of ncds requires global
20:57
coordination and cooperation multis
20:59
sectoral approaches equitable access to
21:02
health care and substantial investment
21:04
in both prevention and treatment
21:07
together we can reduce the global burden
21:09
of non-communicable diseases and create
21:12
a healthier future for all