Why is Oral Poliovirus Vaccine (OPV) preferred over Inactivated Poliovirus Vaccine (IPV)?
Why is Oral Poliovirus Vaccine (OPV) preferred over Inactivated Poliovirus Vaccine (IPV)?
Answer
OPV is preferred over IPV in many settings because it is easier to administer (oral) and provides both systemic and local immunity (in the gut), which helps in preventing the spread of poliovirus in the community. Additionally, OPV is less expensive and can contribute to herd immunity. However, IPV is used in settings where the risk of vaccine-associated paralytic poliomyelitis (VAPP) with OPV is a concern.