When is the Henderson-Hasselbalch equation used?

It is used when: – Designing buffer solutions with specific pH values. – Studying acid-base equilibria in chemical and biological systems. – Analyzing the ionization states of molecules in pharmaceuticals and biochemistry. – Teaching concepts of acid-base chemistry in educational settings. It is most accurate when the concentrations of the acid and conjugate base are significantly higher than the concentration of hydrogen ions, and the solution is dilute.