Topoisomerase: – A. Separates the DNA strands at the origin – B. Keeps the single-stranded DNA regions from coming back together – C. Re-coils the DNA into a helix after replication is complete – D. Breaks DNA backbone to remove tension produced by the helicase – E. Breaks hydrogen bonds between DNA and the RNA primers

Topoisomerase:
– A. Separates the DNA strands at the origin
– B. Keeps the single-stranded DNA regions from coming back together
– C. Re-coils the DNA into a helix after replication is complete
– D. Breaks DNA backbone to remove tension produced by the helicase
– E. Breaks hydrogen bonds between DNA and the RNA primers