Does insulin increase glycogenolysis?

No, insulin does not increase glycogenolysis. In fact, insulin inhibits glycogenolysis. Insulin is released by the pancreas in response to high blood glucose levels and promotes the storage of glucose by activating glycogen synthase and inhibiting glycogen phosphorylase. Glycogen phosphorylase is the enzyme responsible for the breakdown of glycogen into glucose-1-phosphate, and insulin inhibits its activity to prevent glycogen breakdown, ensuring that glucose is stored in cells rather than released into the bloodstream.