Biochemistry 5 Views 1 Answers

Sourav Pan🥇 GoldApril 24, 2025
Are there two Henderson-Hasselbalch equations?
Are there two Henderson-Hasselbalch equations?
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Sourav Pan🥇 GoldMay 15, 2025
There is a single Henderson-Hasselbalch equation, but it can be applied in two contexts: – For acidic buffers: pH = pKa + log10([A⁻]/[HA]), where [A⁻] is the conjugate base and [HA] is the weak acid. – For basic buffers: pOH = pKb + log10([BH⁺]/[B]), where [BH⁺] is the conjugate acid and [B] is the weak base. Alternatively, since pH + pOH = 14, the equation can be adapted accordingly.
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