Streptococcus pneumoniae (S. pneumoniae) is a gram-positive, alpha-hemolytic bacterium.

S. pneumoniae is commonly found in the upper respiratory tract of humans.

It is a leading cause of community-acquired pneumonia, meningitis, and sepsis.

S. pneumoniae produces a polysaccharide capsule, which helps it evade the immune system.

There are over 90 known serotypes of S. pneumoniae, with varying levels of virulence.

S. pneumoniae is transmitted through respiratory droplets, close contact, and fomites.

S. pneumoniae causes a range of diseases, from mild otitis media to life-threatening invasive infections.

S. pneumoniae has developed resistance to several antibiotics, making treatment challenging.

Vaccines (PCV and PPSV) are available to prevent S. pneumoniae infections, especially in high-risk groups.

S. pneumoniae infections are responsible for significant morbidity and mortality worldwide, particularly in children and older adults.